Zimbabwean International Costa Nhamoinesu’s AC Sparta Prague has been handed a trick draw against Italian side Lazio.
Sparta beat 4-0 Krasnodar on aggregate to proceed to the last 16.
Liverpool and Manchester United will face each other in European competition for the first time after being drawn together in the last 16 of the Europa League.
Spurs, meanwhile, face the terrifying task of facing Bundesliga giants Borussia Dortmund.
Here’s the draw in full:
Shakhtar Donetsk v Anderlecht
Basel v Sevilla
Villarreal v Leverkusen
Athletic Bilbao v Valencia
Liverpool v Man Utd
Sparta Praha v Lazio
Dortmund v Tottenham
Fenerbahce v Braga
The last-16 ties will be played on 10 and 17 March.
The final takes place at Basel’s St Jakob-Park on Wednesday, 18 May.