Arsenal and Milan will meet in the Europa League last 16, while favourites Atlético Madrid will entertain Lokomotiv Moscow.

Arsène Wenger’s side were relieved to edge past Swedish side Östersund on Thursday after losing 2-1 in the second leg and their reward will be a meeting with the team they last met at the same stage of the Champions League in 2012. On that occasion, a disastrous 4-0 defeat at San Siro in the first leg virtually ended Arsenal’s hopes of reaching the last eight although they won the home leg 3-0.

Elsewhere, Borussia Dortmund will face Red Bull Salzburg and Atlético Madrid take on Lokomotiv Moscow. Lazio meet Dynamo Kyiv, RB Leipzig have been drawn against Celtic’s conquerors Zenit St Petersburg, CSKA Moscow face Lyon – who will be hosting this year’s final – while fellow Ligue 1 side Marseille tackle Athletic Bilbao and Sporting play Viktoria Plzen.

Round of 16 draw
Lazio (ITA) v Dynamo Kyiv (UKR)
Leipzig (GER) v Zenit (RUS)
Atlético Madrid (ESP) v Lokomotiv Moskva (RUS)
CSKA Moskva (RUS) v Lyon (FRA)
Marseille (FRA) v Athletic Club (ESP)
Sporting CP (POR) v Plzeň (CZE)
Dortmund (GER) v Salzburg (AUT)
AC Milan (ITA) v Arsenal (ENG)